Simple Definition:

Neuropathy is a condition in which there is damage or dysfunction in the nerves [the parts of the body that send messages to the brain]. This can result in various symptoms, such as pain, numbness, and tingling [a feeling like pins and needles]. For example, diabetic neuropathy is a type of neuropathy that occurs in people with diabetes and can cause foot pain and loss of sensation.

Very Simple Definition:

Neuropathy is a condition that affects the nerves and can cause pain or numbness. For example, some people with diabetes may have neuropathy in their feet, which means their feet can hurt or feel numb.